Pain is often described as an uncomfortable sensation that affects both the body and mind as well. It stems from the activation of nociceptors that detect tissue damage. The sensation can range from a slight annoyance to completely debilitating discomfort. In the case of debilitating pain, patients are advised to buy strong painkillers, such as tramadol tablets (Ultram), to help reduce the painful sensations. If you are wondering, what is tramadol and how does it work - it is a synthetically based opioid treatment that is well-known for its potent painkilling properties.

Codeine, an analgesic medication that dates back centuries, is the most commonly used opiate in the world. It was first isolated by a French chemist for its pain-relieving properties. Listed as an essential medication on the World Health Organisation's List of Essential Medicines, this therapeutic is indicated for the treatment of mild to moderate pain. There are different types of pain, such as neuropathic pain, which is a direct result of nerve damage or nociceptive pain, which is a result of damage to body tissue. Pain can be acute or chronic, and more often than not, chronic pain is a symptom of a disorder or disease.

The exact mechanism of action of this medication is not entirely known. Researchers have suggested, though, that opiates affect the signalling pathway of nerve cells. When pain is experienced, such as if you touch something hot for example, the sensory receptors in your fingers 'sense' a message of injury. This message is then sent through the nerve signalling pathway, to the brainstem and spinal cord. After being transmitted to the brain, the brain processes the message and interprets it as an unpleasant feeling of pain.

Pregabalin, also marketed under the brand name Lyrica among others, belongs to a class of medications known as anticonvulsants. This medication is used to reduce or prevent seizures and it can be used alone or in combination with other medications. It has anti-anxiety and pain-relieving effects that make it useful in the treatment of anxiety disorders and various conditions that cause pain.

Before we look at how this medication works, it is important to understand its background as well as its uses, safety and pharmacological effects. Questions that often get asked are what is pregabalin and how does this medication compare with gabapentin 300 mg? Both pregabalin and gabapentin are classified as gabapentinoids that work in a similar way and their pharmacological effects are much alike.

We live in a dynamic, fast-paced and globalised world that has forced us to react and adapt to change more rapidly. Oftentimes, people are expected to live up to the pressures of career, personal and social objectives. More and more people, particularly professionals, are feeling the brunt of managing stress and anxiety on a daily basis. Many people use substances such as alcohol and cigarettes to help manage the stress of their daily lives. Others turn to therapy that often comes at a high financial cost. Luckily, there are solutions that offer an affordable and effective approach to dealing with anxiety.